ABSTRACT
The conventional diagnosis of cholera depends on complex bacteriological procedures. Coagglutination is a simnple, rapid, inexpensive and efficient technique for the presumptive diagnosis of cholera. Of 840 fecal samples from suspected cases of cholera examined at Tabatinga (State of Amazonas, Brazil) 31 (3.6%) were confirmed by culture and 29 of then were also positive by the coagglutination test performed directly on the fecal enrichment broth (alkaline peptone water). About 90% of the positive coagglutination results were obtained after-5-h incubation at 37 grade C and the sensitivity, specificity and accuracy of the method were 93.5%, 99% and 98.8%, respectively. relative to the culture results, coagglutination yielded two false-negative and eight false-positive results. The coagglutination test for cholera can provide a rapid and reliable tool for epidemiological studies and for the planning of more effective measures against cholera